Aged Garlic Extract (Age)

Some supplements roar into your life with wild claims and neon promises. Others hum quietly in the background, building a case year after year, study after study. Aged Garlic Extract (AGE) is firmly in the latter camp.

Not raw garlic. Not garlic oil. Aged garlic—fermented for months—produces unique, stable compounds like S-allyl cysteine that change the game. Better bio-availability, reduced harshness, less vampire-repelling aftershocks.

But is it worth adding to your stack? Let’s run it through the Evidence-Based Truth Claim Scale (ETCS) and find out.

ETCS Score: 80/100 (Strong Evidence)

RCTs and meta-analyses consistently show that AGE can reduce systolic and diastolic blood pressure by 5–10 mmHg—a clinically meaningful shift.

• Enhances nitric oxide production

• Improves endothelial function

• Reduces arterial stiffness

Bottom line? If you’re fighting the silent war of hypertension, AGE gives you another weapon—no prescription required.

ETCS Score: 70/100 (Moderate-to-Strong Evidence)

AGE modestly improves lipid profiles:

• Lowers total cholesterol and LDL (~5–10%)

• Occasionally raises HDL

Not a magic bullet—but a steady nudge in the right direction, especially for people starting from sub-optimal baselines.

ETCS Score: 65/100 (Moderate Evidence)

Studies suggest that AGE can enhance natural killer (NK) cell activity, strengthen T-cell responses, and shorten cold duration.

• Some small human studies

• Stronger evidence in animal models

Useful as a subtle immune tune-up—not a replacement for sleep, sunlight, or sanity.

ETCS Score: 75/100 (Strong Evidence)

One of AGE’s most compelling benefits: slowing the progression of coronary artery calcium scores.

• Lower plaque progression = lower heart attack risk

• Antioxidant, anti-inflammatory, and endothelial protective effects

It’s one thing to feel better. It’s another to be measurably aging slower from the inside out.

ETCS Score: 85/100 (Near-Certain)

Safety studies look excellent:

• Well-tolerated even at higher doses

• Minimal drug interactions (mild caution with blood thinners)

• No significant GI upset—a major upgrade over raw garlic

When a supplement has both clinical effects and excellent tolerability? That’s rare air.

Is Aged Garlic Extract worth it?

If you want to quietly, consistently upgrade your cardiovascular health, bolster your immune system, and age a little more gracefully, yes.

AGE isn’t loud. It isn’t flashy. It doesn’t promise to fix your whole life by next Tuesday.

It’s just solid science, small daily gains, and low risk — the hallmarks of compounding health.

Final ETCS Score for Aged Garlic Extract: 76/100

The effects of aged garlic extract in older endurance athletes

In this 12-week randomized controlled trial in 75 older endurance athletes (ages 40–65), supplementing with aged garlic extract improved some aerobic exercise metrics.

Disclaimer

The health-related content on Domo Futu reflects my personal experiences, years of research, and a lifelong interest in health, performance, and longevity. My journey into this world kicked off when I was 12 years old with two books: Eat to Win: The Sports Nutrition Bible