Uniswap (UNI) and Aave (AAVE) both fall 10.4%, leading index lower.
Sep 22, 2025, 1:48 p.m.

CoinDesk Indices presents its daily market update, highlighting the performance of leaders and laggards in the CoinDesk 20 Index.
The CoinDesk 20 is currently trading at 4042.07, down 5.4% (-229.32) since 4 p.m. ET on Friday.
None of the 20 assets is trading higher.

Leaders: BTC
(-2.3%)
and BCH
(-5.1%)
.
Laggards: UNI
(-10.4%)
and AAVE
(-10.4%)
.
The CoinDesk 20 is a broad-based index traded on multiple platforms in several regions globally.
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