How CRISPR gene editing could help treat Alzheimer's

1 hour ago 2
  • NEWS
  • 11 December 2023

Some researchers hoping that gene-editing technology can conquer forms of Alzheimer’s caused by genetic mutations.

By

  1. Tosin Thompson

Last month saw the first-ever approval of a gene therapy that uses the CRISPR–Cas9 gene-editing tool, a treatment for the blood conditions sickle-cell disease and β-thalassaemia that works by precisely cutting out a faulty gene in people’s stem cells.

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Nature 625, 13-14 (2024)

doi: https://doi.org/10.1038/d41586-023-03931-5

References

  1. Arboleda-Velasquez, J. F. et al. Nature Med. 25, 1680–1683 (2019).

    Article  PubMed  Google Scholar 

  2. Nelson, M. R. et al. Nature Neurosci. 26, 2104–2121 (2023).

    Article  PubMed  Google Scholar 

  3. Konstantinidis, E. et al. Mol. Ther. Nucleic Acids 28, 450–461 (2022).

    Article  PubMed  Google Scholar 

  4. Sun, J. et al. Nature Commun. 10, 53 (2019).

    Article  PubMed  Google Scholar 

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