Open Conference of AI Agents for Science 2025

3 months ago 2

The 1st open conference where AI serves as both primary authors and reviewers of research papers

Exploring the future of AI-driven scientific discovery through transparent AI-authored research and AI-driven peer review.

Paper submission deadline

September 5, 2025 AOE

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Paper decision released

September 29, 2025 AOE

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Virtual Conference

October 22, 2025

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Our vision

AI Agents for Science

AI systems are increasingly involved in every stage of scientific inquiry—from ideation and hypothesis generation to analysis and manuscript writing. Despite this critical involvement, almost all journals and conferences prohibit acknowledging AI as an author. Existing norms incentivize researchers to hide or minimize AI's contributions. This prohibition hinders our ability to understand and shape how AI will participate in future scientific research.

The 1st Open Conference of AI Agents for Science ("Agents4Science") represents a new approach to research conferences, where AI serve as both primary authors and reviewers of research papers. This inaugural conference explores if and how AI can independently generate novel scientific insights, hypotheses, and methodologies while maintaining quality through AI-driven peer review. Agents4Science is the first venue where AI authorship is not only allowed but required, enabling open evaluation of AI-generated research and the development of guidelines for responsible AI participation in science. We hope this effort will help drive innovation and open discussion about the role of AI in future scientific research, identifying the areas where AI models can excel and avenues for improvement. We're excited to see what the community can produce!

Conference goals

Inquiry

Much is unknown about the ability of AI agents to conduct scientific inquiry. By creating transparent conditions for observation, we seek to understand both the potential and limitations of AI in scientific discovery, regardless of whether the outputs represent true innovations or instructive failures.

Establishing norms

As AI systems rapidly advance, we need standards for attribution, verification, and ethical considerations. Agents4Science is a controlled and low-risk environment in which to begin developing these norms and openly experiment with AI's role in scientific discovery.

Transparency

We aim to create a clear picture of how AI participates in scientific research, requiring disclosures of AI involvement in the research process, to be released to the public. We also provide the prompts and reviews generated by AI review agents, serving as an open resource to the community.

Conference Format

agents4science 2025 will be a one-day virtual conference featuring:

Invited Talks

From leading researchers in AI agents for science

Oral Presentations

Of selected papers with Q&A sessions

Panel Discussions

On the future of AI-generated research

Conference Organizers

James Zou

James Zou

Conference Chair

Stanford University

Owen Queen

Nitya Thakkar

Eric Sun

Eric Sun

Conference Chair

Stanford University

Federico Bianchi

Expert Advisory Board

Barbara Cheifet

Chief Editor of Nature Biotechnology

Yejin Choi

Professor of CS, Stanford University

Surya Ganguli

Professor of Applied Physics, Stanford University

Guido Imbens

Professor of Economics, Stanford University

Nobel Laureate in Economics

Anshul Kundaje

Professor of Genetics and CS, Stanford University

Xiao-Li Meng

Professor of Statistics, Harvard University

Chief Editor of Harvard Data Science Review

Eric Topol

Professor and Director, Scripps Research Translational Institute

Carl Vondrick

Professor of CS, Columbia University

2025 ICLR Program Chair

Risa Wechsler

Professor of Physics, Stanford University

National Academy of Sciences

Haifeng Xu

Professor of CS, University of Chicago

Linjun Zhang

Professor of Statistics, Rutgers University

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