Robotic system takes chemistry into hyperspace

1 month ago 3
  • NEWS AND VIEWS
  • 24 September 2025

Exploring multidimensional ‘landscapes’ of chemical reactions provides rich insights into how they work, and might even enable the discovery of new forms of reactivity.

By

  1. William E. Robinson
    1. William E. Robinson is at Radboud University in Nijmegen, the Netherlands, and the Big Chemistry consortium in the Netherlands.

When people think of a reaction to synthesize a new chemical compound, they might imagine an equation consisting of one or two reactants on the left-hand side, leading to a single product compound on the right. Around the reaction arrow, details of the conditions might be given: a single temperature, catalyst concentration or reaction time, for instance.

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Nature 645, 861-862 (2025)

doi: https://doi.org/10.1038/d41586-025-02821-2

References

  1. Jia, Y. et al. Nature 645, 922–931 (2025).

    Article  Google Scholar 

  2. Leonov, A. I. et al. Nature Commun. 15, 1240 (2024).

    Article  PubMed  Google Scholar 

  3. Dai, T. et al. Nature 635, 890–897 (2024).

    Article  PubMed  Google Scholar 

  4. Ha, T. et al. Sci. Adv. 9, eadj0461 (2023).

    Article  PubMed  Google Scholar 

  5. Slattery, A. et al. Science 383, eadj1817 (2024).

    Article  PubMed  Google Scholar 

  6. Rohrbach, S. et al. Science 377, 172–180 (2022).

    Article  PubMed  Google Scholar 

  7. Back, S. et al. Digit. Discov. 3, 23–33 (2024).

    Article  PubMed  Google Scholar 

  8. Schäfer, F., Lückemeier, L. & Glorius, F. Chem. Sci. 15, 14548–14555 (2024).

    Article  PubMed  Google Scholar 

  9. Robinson, W. E., Daines, E., van Duppen, P., de Jong, T. & Huck, W. T. S. Nature Chem. 14, 623–631 (2022).

    Article  PubMed  Google Scholar 

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Competing Interests

The author declares no competing interests.

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